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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARNTL All Species: 14.85
Human Site: S42 Identified Species: 29.7
UniProt: O00327 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00327 NP_001025443.1 626 68762 S42 C N R K R K G S S T D Y Q E S
Chimpanzee Pan troglodytes XP_001171687 626 68743 S42 C N R K R K G S S T D Y Q E S
Rhesus Macaque Macaca mulatta XP_001095200 626 68713 S42 C N R K R K G S S T D Y Q E S
Dog Lupus familis XP_851850 634 69695 D49 S S T D Y Q L D D F S F E E S
Cat Felis silvestris
Mouse Mus musculus Q9WTL8 632 69433 D49 S A T D Y Q L D D F A F E E S
Rat Rattus norvegicus Q9EPW1 626 68597 S42 C N R K R K G S A T D Y Q E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507514 398 44707
Chicken Gallus gallus Q9I8T7 633 69419 D49 S S T D Y Q L D G F P F E E G
Frog Xenopus laevis NP_001089024 627 68721 Q47 K G S L S D Y Q A D G F P F D
Zebra Danio Brachydanio rerio Q9DG12 737 80954 A48 R G G K R R S A G M D F D D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61734 413 47551
Honey Bee Apis mellifera XP_001121441 739 82052 Y132 Q Q Q Q Q G S Y Y S L S A V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 99.8 97.6 N.A. 97.3 98.2 N.A. 52.8 93.2 85.8 31.6 N.A. 35.2 42.6 N.A. N.A.
Protein Similarity: 100 100 99.8 98.4 N.A. 97.7 98.8 N.A. 55.4 95 91 49.9 N.A. 48.5 55.6 N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 13.3 93.3 N.A. 0 6.6 0 20 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 33.3 100 N.A. 0 33.3 13.3 46.6 N.A. 0 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 9 17 0 9 0 9 0 0 % A
% Cys: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 25 0 9 0 25 17 9 42 0 9 9 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 25 59 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 25 0 42 0 9 0 % F
% Gly: 0 17 9 0 0 9 34 0 17 0 9 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 42 0 34 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 25 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % P
% Gln: 9 9 9 9 9 25 0 9 0 0 0 0 34 0 9 % Q
% Arg: 9 0 34 0 42 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 25 17 9 0 9 0 17 34 25 9 9 9 0 0 50 % S
% Thr: 0 0 25 0 0 0 0 0 0 34 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 25 0 9 9 9 0 0 34 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _